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细胞有增殖、分化和凋亡3方面的特性.在维持正常组织的生长平衡过程中,细胞增殖、分化与凋亡3者相互协调,共同调节,其中细胞周亡(apoptosis)对细胞衰老与更新、保持细胞数目的相对恒定方面起着重要作用.肿瘤不仅是增殖和分化异常的疾病,同时也是凋亡异常的疾病,治疗肿瘤就是杀伤和清除肿瘤细胞,诱导肿瘤细胞凋亡是治疗肿瘤的一条有效途径,临床上用的化疗、放疗和热疗等方法的作用机制之一就是引发肿瘤细胞凋亡.肿瘤坏死因子(TNF)是一种由活化的巨噬细胞或单核细胞分泌的具有多种生物学效
The cells have the characteristics of proliferation, differentiation and apoptosis. In the process of maintaining the balance of normal tissues, the three cell proliferation, differentiation and apoptosis are coordinated with each other, and they are jointly regulated. Among them, apoptosis is associated with cell senescence and renewal. Maintaining a relatively constant cell number plays an important role. Tumors are not only diseases with abnormal proliferation and differentiation, but also diseases with abnormal apoptosis. Treatment of tumors kills and eliminates tumor cells, and induction of tumor cell apoptosis is a treatment of tumors. One of the effective mechanisms, one of the mechanisms of action of chemotherapy, radiotherapy, and hyperthermia used clinically is to induce apoptosis in tumor cells. Tumor necrosis factor (TNF) is a type of secreted by activated macrophages or monocytes. Biological effects