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目的采用床边头颅B超早期诊断早产儿脑室周围-脑室内出血(PVH-IVH),分析其相关危险因素。方法住院的443例早产儿为研究对象,Logistic回归分析影响PVH-IVH的危险因素。结果单因素分析显示:胎龄、出生体质量、机械通气、血细胞比容、血红蛋白、低体温、生后感染、呼吸暂停、PaCO2在PVH-IVH组和无PVH-IVH组之间差异有统计学意义(P<0.05)。Logistic回归分析显示:胎龄低、机械通气和血红蛋白水平低是早产儿PVH-IVH的危险因素,胎龄低和呼吸暂停是重度PVH-IVH的危险因素。结论胎龄低、机械通气和血红蛋白水平低是早产儿发生PVH-IVH的危险因素。
OBJECTIVE To evaluate the risk factors of periventricular-ventricular hemorrhage (PVH-IVH) in preterm infants by bedside cranial ultrasound B-ultrasonography. Methods 443 preterm infants were enrolled in this study. Logistic regression analysis was used to analyze the risk factors affecting PVH-IVH. Results Univariate analysis showed that there was statistical difference in gestational age, birth weight, mechanical ventilation, hematocrit, hemoglobin, hypothermia, postnatal infection, apnea, PaCO2 between PVH-IVH group and no PVH-IVH group Significance (P <0.05). Logistic regression analysis showed that low gestational age, low mechanical ventilation and hemoglobin levels were risk factors for PVH-IVH in preterm infants, and low gestational age and apnea were risk factors for severe PVH-IVH. Conclusions Low gestational age, low mechanical ventilation and low hemoglobin levels are risk factors for PVH-IVH in preterm infants.