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目的探讨良恶性胸腔积液的临床和相关实验室特点。方法主要从结核性和肿瘤性两组的胸腔积液的临床表现、实验室常规的检测指标入手。结果肿瘤性胸腔积液以血性为多 ,占 5 4.2 % ;且癌胚抗原 (CEA )≥ 2 0 ng/ml者之阳性率高于结核组 ,特异度为96.43 % (P <0 .0 1) ;胸水 LDH/血清 LDH的测定 ,其结核性胸腔积液未见大于 3 .0 ,与肿瘤性胸腔积液比较 ,有显著性差异 (P<0 .0 1) ;当积液的 p H>7.4时 ,应高度疑及恶性可能 ,其敏感度为 75 % (P<0 .0 1)。结论通过胸腔积液的临床表现及实验室多项指标的联合检测 ,有助于良恶性胸腔积液的诊断与鉴别诊断
Objective To investigate the clinical and related laboratory characteristics of benign and malignant pleural effusions. Methods The main clinical manifestations of tuberculous and neoplastic two groups of pleural effusion, laboratory routine test indicators to start. Results The positive rate of tumorous pleural effusion was 5.22%, and the positive rate of carcinoembryonic antigen (CEA) ≥ 20 ng / ml was higher than that of tuberculosis group with a specificity of 96.43% (P <0.01) ); Pleural effusion LDH / serum LDH determination, the tuberculous pleural effusion no more than 3.0, and the tumor pleural effusion compared to a significant difference (P <0. 01); when the fluid p H > 7.4 should be highly suspicious and malignant possible, the sensitivity was 75% (P <0. 01). Conclusion Through the clinical manifestations of pleural effusion and laboratory joint detection of multiple indicators, it is helpful for the diagnosis and differential diagnosis of benign and malignant pleural effusions