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近年来,大多数临床试验表明,急性心肌梗塞(AMI)后病人,早期开始β阻滞剂治疗可以降低死亡率。兹就近年来国外研究进展作一扼要介绍。β阻滞剂用于梗塞急性期的临床试验 May等复习文献报告了16个急性期试验,大多数病人于住院后尽可能早期开始治疗。其中8个试验(包括口服方案5个,静注方案3个)β阻滞剂治疗组较安慰剂对照组的死亡率降低,但只有一个试验两组差别在统计学上有显
In recent years, most clinical trials have shown that early-onset beta-blocker therapy can reduce mortality in patients after acute myocardial infarction (AMI). I hereby give a brief introduction on the progress of foreign studies in recent years. Beta blockers for clinical trials in the acute phase of infarction May et al Review the literature reporting 16 acute phase trials, with most patients starting treatment as soon as possible after hospitalization. Eight of these trials (5 in the oral regimen, 3 in the intravenous regimen) decreased mortality compared with placebo in the β-blocker group, but only one of the two groups showed statistically significant differences