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目的：比较辛伐他汀与多烯康降血脂的疗效。方法：血胆固醇（ＴＣ）浓度≥５．８５ ｍｍｏｌ．Ｌ－１者６０例，随机分为２组：辛伐他汀组３０例，男性１４例，女性 １６例；年龄 ６３ ａ± ｓ １２ ａ。用辛伐他汀 ５ｍｇ，ｐｏ，ｑｄ。多烯康组３０例，男性１４例，女性１６例，年龄 ６３ ａ± １１ａ。用多烯康胶囊 ３粒， ｐｏ， ｔｉｄ。２组疗程均为 １ｍｏ。结果：辛伐他汀治疗后血ＴＣ，ＬＤＬ－Ｃ浓度明显降低，ＨＤＬ－Ｃ浓度升高差别有非常显著意义（Ｐ＜０．０１），ＴＧ则下降不明显（Ｐ＞０．０５）。多烯康治疗后，仅血ＴＣ下降有非常显著意义（Ｐ＜０．０１）。组间比较，血ＴＣ，ＬＤＬ－Ｃ浓度的下降差别有非常显著意义（ Ｐ＜ ０．０１）。结论：辛伐他汀疗效优于多烯康。
Objective: To compare the efficacy of simvastatin with doemelin in lowering blood fat. Methods: Blood cholesterol (TC) concentration of ≥ 5.85 mmol. Sixty patients with L-1 were randomly divided into two groups: 30 patients in simvastatin group, 14 males and 16 females; aged 63 ± 12 s. Simvastatin 5mg, po, qd. Duoxikang group of 30 cases, 14 males and 16 females, age 63 a ± 11a. With multi-eikang capsule 3, po, tid. 2 groups of treatment are 1mo. Results: After treatment with simvastatin, TC and LDL-C levels in blood were significantly decreased, and HDL-C concentrations were significantly increased (P <0.01). However, TG was not significantly decreased (P> 0.05). After treatment with polyene, blood TC decreased only very significant (P <0.01). The difference between the two groups was significant (P <0.01). Conclusion: Simvastatin is better than doemecan.