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1977～1988年纤支镜检查3975例,其中120例临床和初次检查肺癌可疑,但未获得病理或细胞学确诊而进行纤支镜复查。结果:肺癌确诊32例(假阴性26.6％),可疑10例。产生假阴性的原因是多方面的,如取材不当,组织过少,严重挤压及标本处理不当等。纤支镜复查对临床和初次检查肺癌可疑者很有价值,复查间期1～3周为宜,为减少假阴性进行探讨。
From 1977 to 1988, 3975 cases were examined by fiberbronchoscopy, of which 120 cases were suspected of being clinically and initially examined for lung cancer, but were not reviewed for pathology or cytology and were subjected to bronchoscopy. Results: Thirty-two patients with lung cancer were diagnosed (26.6% false negative), and 10 were suspicious. There are many reasons for false negatives, such as improper materials, too few tissues, severe crushing, improper handling of specimens, etc. The bronchoscopy review is very valuable for clinical and initial examination of suspicious persons with lung cancer. It is advisable to review the interval between 1 and 3 weeks, in order to reduce false negatives.