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目的研究依达拉奉联合银杏叶注射液对急性脑梗死患者血清C反应蛋白(hs-CRP)水平和血液流变学的影响并探讨其与临床疗效的关系。方法治疗组予以常规措施并依达拉奉联合银杏叶注射液治疗,对照组单用银杏叶注射液治疗。观察治疗前后血清hs-CRP水平和血液流变学的变化及临床疗效。结果hs-CRP浓度较治疗前有降低,但治疗组降低较对照更显著;各组患者治疗后血液流变学指标均有改善,与治疗前比较差异有统计学意义,但治疗组的改善更为明显(P<0.01)。治疗组的总有效率及显效率均高于对照组(P<0.05)。结论依达拉奉联合银杏叶注射液治疗可显著降低急性脑梗死患者血清hs-CRP水平,改善血液流变学指标,对急性脑梗死有较好治疗作用。
Objective To investigate the effect of edaravone and ginkgo biloba injection on serum C-reactive protein (hs-CRP) level and hemorheology in patients with acute cerebral infarction and to explore the relationship between edaravone and clinical efficacy. Methods The treatment group was given routine treatment and edaravone combined with ginkgo biloba injection, while the control group was treated with ginkgo biloba injection alone. Changes of serum hs-CRP level and hemorheology before and after treatment were observed and the clinical effects were observed. Results The concentration of hs-CRP was lower than that before treatment, but the reduction in treatment group was more significant than that in control group. The indexes of hemorheology were improved in all groups after treatment, with significant difference compared with those before treatment, but the treatment group improved more (P <0.01). The total effective rate and effective rate of the treatment group were higher than the control group (P <0.05). Conclusion Edaravone combined with Ginkgo biloba injection can significantly reduce the serum hs-CRP levels in patients with acute cerebral infarction, improve blood rheology indicators, the treatment of acute cerebral infarction has a better effect.