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本文应用扫描电镜技术及形态计量学方法，对从平原移居到高原（海拔3900米）的实验家兔外周血红细胞进行了研究。实验分为平原组，高原给药组，高原对照组。结果发现：高原给药组家兔红细胞的直径和体积均小于高原对照组，显示极显著住意义，（P＜0．01）。高原给药组的红细胞体积与高原对照组相比，平均减少8．4％左右。高原给药组红细胞直径（Y）与高原对照组红细胞直径（X）呈正相关，r=0．58，P＜0．05。另外高原给药组红细胞直径（Y）与红细胞计数（x）也呈正相关，r=0．67，P＜0．05。结果提示异叶青兰不仅可降低由缺氧所引起的红细胞体积增大，而且可降低红细胞的数量，从而降低血液的粘滞性，改善血循环。
In this paper, we studied the peripheral blood red blood cells of rabbits who migrated from plain to plateau (3900m above sea level) using scanning electron microscopy (SEM) and morphometry. The experiment was divided into plain group, plateau administration group and plateau control group. The results showed that the diameter and volume of rabbit erythrocytes in the plateau group were all less than those in the plateau control group, indicating significant significance (P <0.01). Compared with the plateau control group, the volume of erythrocytes in plateau-administered group decreased by about 8.4% on average. There was a positive correlation between the diameter of erythrocytes (Y) and the diameter of erythrocytes (X) in plateau control group (r = 0.58, P <0.05). In addition, there was a positive correlation between erythrocyte diameter (Y) and erythrocyte count (x) in plateau group (r = 0.67, P <0.05). The results suggest that Isatis indigotica can not only reduce the volume of red blood cells caused by hypoxia, but also reduce the number of red blood cells, thereby reducing blood viscosity and improve blood circulation.