,Gene editing using CRISPR/Cas9: implications for dual-use and biosecurity

• 作 者: Diane DiEuliis James Giordano
• 机 构: Center for the Study of Weapons of Mass Destruction, National Defense University, Washington, DC 200
• 出 处: 蛋白质与细胞
• 发表日期: 2018年3期

We have read with interest the recent paper by Kang, et al (2017), addressing clinical and ethical issues related to the safe and responsible use of CRISPR/Cas. The authors provide a number of important considerations about the current capabilities offered by this novel gene-editing tool, including germ line editing in embryos, and potential diverse uses in adult human applications. The authors posit that the tool in of itself does not represent a threat, and that periodic assessment will ensure its responsible use.