论文部分内容阅读
本文用放射免疫方法测定６０例糖尿病病人及２３例正常人尿白蛋白排泄率，血ＴｘＢ２，尿ＴｘＢ２。结果显示３１％糖尿病病人伴微量白蛋白尿。微量白蛋白尿病人、非微量白蛋白尿病人及正常人血ＴｘＢ２三者间无显著性差异（Ｐ＞０．０５）；微量白蛋白尿病人尿ＴｘＢ２排泄率显著高于非微量白蛋白尿病人和正常人（Ｐ＜０．０５），而非微量白蛋白尿病人与正常人间无显著差别（Ｐ＞０．０５）。提示糖尿病病人伴微量白蛋白尿者肾脏ＴｘＡ２合成增加，尿ＴｘＢ２测定可反映肾脏ＴｘＡ２的代谢变化，血浆ＴｘＢ２测定不能反映肾脏（局部ＴｘＡ２的代谢）变化
In this paper, 60 cases of diabetic patients and 23 cases of normal urine urinary albumin excretion rate, blood TxB2, urinary TxB2. The results showed that 31% of diabetic patients with microalbuminuria. Microalbuminuria patients, non-microalbuminuria patients and normal blood TxB2 between the three no significant difference (P> 0.05); microalbuminuria urinary TXB2 excretion rate was significantly higher than non-microalbuminuria patients And normal (P <0.05), but no difference between patients with microalbuminuria and normal (P> 0.05). Suggesting diabetic patients with microalbuminuria increased kidney TxA2 synthesis, urinary TxB2 determination can reflect the metabolic changes of the kidney TxA2, plasma TxB2 determination does not reflect the changes in the kidney (local TxA2 metabolism)