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目的:以单用氨甲蝶呤(MTX)为对照,探讨氨甲蝶呤配伍米非司酮在异位妊娠保守治疗中的应用价值。方法:将该院2003~2006年122例血β-HCG≤2 000 mIU/ml的未破裂的异位妊娠患者分别给予MTX联合米非司酮(甲组)和单用MTX(乙组)治疗,比较二者的疗效。结果:甲组成功率86.9%(53/61),乙组成功率70.5%(43/61),两者比较差异有显著性(P<0.05)。治疗成功患者甲组血β-hCG转阴时间与乙组比较有显著性差异(P<0.05),两组毒副反应无差异(P>0.05)。结论:MTX配伍米非司酮治疗异位妊娠的效果优于单用MTX。
Objective: To evaluate the value of methotrexate combined with mifepristone in the conservative treatment of ectopic pregnancy with methotrexate alone (MTX) as a control. Methods: 122 untreated ectopic pregnancy patients with blood β-HCG≤2,000 mIU / ml in 122 cases from 2003 to 2006 were given MTX combined with mifepristone (group A) and MTX alone (group B) , Compare the efficacy of the two. Results: The success rate of Group A was 86.9% (53/61), Group B was 70.5% (43/61), the difference was significant (P <0.05). The successful treatment of patients with a group of blood β-hCG negative conversion time compared with the B group was significantly different (P <0.05), two groups of no side effects (P> 0.05). Conclusion: MTX with mifepristone in the treatment of ectopic pregnancy better than MTX alone.