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本实验以Wistar大鼠为研究对象，对大鼠红细胞CAT（过氧化氢酶）活性，全血GSH－Px（谷胱甘肽过氧化物酶）活性，血浆LPO（过氧化脂质）进行测定。观察上述指标的随龄变化，甘草对老年大鼠体内上述指标的影响。结果表明，大鼠体内的抗氧化酶CAT、GSH－Px活性在其成长阶段随龄上升（P＜0．01），在衰老阶段随龄下降（P＜0．01）。自由基代谢产物LPO含量在血浆中随龄增加（P＜0．01）甘草水前剂能提高老年大鼠全血CAT、GSH－Px活性（P＜0．01），降低血浆LPO含量（P＜0．01）。不同用药时间（15，30，45d）对上述指标的动态变化无明显影响（P＜0．05）,提示甘草具有抗衰老作用。
In this experiment, Wistar rats were used as the study object. The red blood cell CAT (catalase) activity, whole blood GSH-Px (glutathione peroxidase) activity, plasma LPO (lipid peroxide) were measured. . Observed the changes of the above indicators with age, the effects of licorice on the above indicators in aged rats. The results showed that the activities of antioxidant enzymes CAT and GSH-Px in rats increased with age in the growth phase (P<0.01), and decreased with age in the aging phase (P<0.01). The LPO content of free radical metabolites increased in plasma with age (P<0.01). Glycyrrhizic water pro-promoter increased the activity of CAT and GSH-Px in whole blood of aged rats (P<0.01), and decreased the plasma LPO content (P<0.01). <0.01). The different time (15, 30, 45 d) had no significant effect on the dynamic changes of the above indicators (P<0.05), suggesting that licorice has anti-aging effects.