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目的 总结河北省临床诊断为严重急性呼吸综合征 (SARS)病例的病情发展规律 ,探讨其治疗与预后的关系。方法 采用流行病学调查方法 ,到各定点医院如实采集确诊SARS病例 2 13例 ,录入计算机 ,用Access建立《SARS病历摘要表》数据库 ,以SPSS 11.5版统计软件进行数据整理和分析。结果 ① 2 13例中有明显SARS接触者194例 (91.1% ) ,年龄 18～ 5 9岁者 196例 ,占 92 .0 % ;② 2 13例患者均有发热 ,伴有干咳 190例 (89.2 % ) ,乏力 71例(33.3% ) ,气短 4 9例 (2 3.0 % ) ;2 13例患者中有 6 9例 (32 .4 % )白细胞下降 ,血小板减少者 37例 (17.4 % ) ,但未见明显出血倾向 ;胸片表现早期有异常 ,一般以点片状影、单侧或双侧肺叶的炎性浸润性阴影为主 ;③ 2 13例SARS患者 ,单纯西医药治疗 84例 ,中西医结合治疗 12 9例 ;④ 2 13例SARS患者中治愈 2 0 2例 ,治愈率 94 .8% ;死亡 11例 ,病死率5 .2 %。结论 SARS有较强的传染性 ,传播速度快 ,人群普遍易感 ,发病有家庭和医院聚集传播的现象 ,2 13例SARS治疗效果理想。
Objective To summarize the clinical development of severe acute respiratory syndrome (SARS) in Hebei Province and to explore the relationship between the treatment and prognosis. Methods According to the epidemiological survey method, 213 confirmed cases of SARS were collected truthfully from various designated hospitals. The data were collected in the computer and the database of SARS medical records summary tables was set up by Access. The data were analyzed and sorted by SPSS 11.5 statistical software. Results ① There were 194 cases (91.1%) with obvious SARS contact in 213 cases, and 196 cases (92.0%) were aged 18-59 years old. ② There were 190 cases with fever (89.2 ), Fatigue in 71 cases (33.3%), shortness of breath in 49 cases (2.03%); 2 of 13 patients, 69 (32.4%) leukopenia and thrombocytopenia in 37 cases (17.4%), No obvious bleeding tendency; chest X-ray showed early abnormalities, usually with patchy shadow, unilateral or bilateral inflammatory infiltration shadow of the lung lobes mainly; ③ 213 cases of SARS patients, simple Western medicine treatment of 84 cases, 129 cases of SARS were cured.220 cases were cured, the cure rate was 94.8%; 11 cases died, the case fatality rate was 5.2%. Conclusions SARS has strong contagiousness, rapid transmission, general population susceptibility, incidence of home and hospital aggregation and transmission, and satisfactory results of 2 13 SARS cases.