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[目的]研究康复新液与埃索美拉唑联合治疗老年人反流性食管炎的疗效。[方法]将胃镜检查确诊的68例反流性食管炎老年患者随机分为两组,治疗组34例,口服康复新液10 ml,每日3次,埃索美拉唑20 mg,每日2次,口服;对照组34例,口服埃索美拉唑20 mg,每日2次。治疗前、治疗4周及8周分别记录临床症状,疗程结束后,胃镜复查评估反流性食管炎治疗情况。[结果]治疗4周后治疗组临床症状和胃镜下有效率分别为47.1%和58.8%;对照组分别为41.2%和47.1%(P>0.05)。治疗8周后,治疗组上述指标分别为91.25%,94.1%;对照组分别为67.6%和76.5%(P<0.05)。两组在用药期间,不良反应少,均有良好的耐受性。[结论]康复新液联合埃索美拉唑治疗老年人中、重度反流性食管炎,可提高食管炎的治愈率和有效率,缩短反流性食管炎的治愈时间。
[Objective] To study the curative effect of Kangfuxin and esomeprazole in the treatment of reflux esophagitis in the elderly. [Methods] 68 elderly patients with reflux esophagitis diagnosed by gastroscopy were divided into two groups at random. The treatment group consisted of 34 patients with 10 ml oral rehabilitation fluid 3 times a day, esomeprazole 20 mg daily 2 times, oral; control group of 34 patients, oral esomeprazole 20 mg, 2 times a day. Before treatment, the treatment of 4 weeks and 8 weeks were recorded clinical symptoms, end of treatment, gastroscopy review evaluation of reflux esophagitis treatment. [Results] After 4 weeks of treatment, the effective rate of clinical symptoms and endoscopy in the treatment group were 47.1% and 58.8% respectively; the control group was 41.2% and 47.1% respectively (P> 0.05). After 8 weeks of treatment, the above indexes in the treatment group were 91.25% and 94.1% respectively, while those in the control group were 67.6% and 76.5% respectively (P <0.05). Two groups in the medication period, less adverse reactions, have good tolerance. [Conclusion] Kangfuxin combined with esomeprazole in the treatment of moderate and severe reflux esophagitis in the elderly can improve the cure rate and effective rate of esophagitis and shorten the cure time of reflux esophagitis.