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目的 :本文旨在探讨生理性DGR发生的规律及正常参数值 ,对DGR与慢性浅表性胃炎的关系进行了研究。方法 :1 8例无任何临床症状的健康自愿者 ,1 6例慢性浅表性胃炎患者 ,用Bilitec 2 0 0 0行胃内 2 4h胆汁监测。结果 :生理性DGR胆红素光吸收值 >0 .1 4的总时间百分比 ,均值为 1 0 .4± 9.88,95 %参考值正常上限值为 35 .6 %。慢性浅表性胃炎组与健康对照组胆汁反流各项指标比较 ,无显著性差异 (P >0 .0 5)。结论 :正常健康人群在直立、仰卧、餐时、餐后不同阶段具有不同的十二指肠胃反流 ,睡眠时反流较其他阶段明显增多 (P<0 .0 5) ,且个体差异较大。正常健康对照组与慢性浅表性胃炎比较 ,无显著性差异 (P >0 .0 5) ,胃炎是否与胆汁相关 ,有待进一步研究
OBJECTIVE: This study aimed to investigate the regularity and physiological parameters of physiological DGR and to study the relationship between DGR and chronic superficial gastritis. Methods: A total of 18 healthy volunteers without clinical symptoms and 16 patients with chronic superficial gastritis were enrolled in this study. Results: The mean percentage of physiological DGR bilirubin absorbance> 0.14, with a mean of 1.04 ± 9.88 and a 95% upper limit of normal reference value of 35.6%. Chronic superficial gastritis group and healthy control group bile reflux indicators, there was no significant difference (P> 0.05). Conclusion: The normal healthy population has different duodenogastric reflux in different stages of erection, supine, meal and postprandial period, and the reflux during sleep is significantly increased compared with other stages (P <0.05) . Compared with chronic superficial gastritis, there was no significant difference between normal healthy control group and chronic superficial gastritis (P> 0.05), and gastritis was associated with bile, which needs further study