,Circadian rhythms in liver metabolism and disease

来源 :Acta Pharmaceutica Sinica B | 被引量 : 0次 | 上传用户:tank2203555
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Mounting research evidence demonstrates a significant negative impact of circadian disruption on human health. Shift work, chronic jet lag and sleep disturbances are associated with increased incidence of metabolic syndrome, and consequently result in obesity, type 2 diabetes and dyslipidemia.Here, these associations are reviewed with respect to liver metabolism and disease. Mounting research evidence demonstrates a significant negative impact of circadian disruption on human health. Shift work, chronic jet lag and sleep disturbances are associated with increased incidence of metabolic syndrome, and that result result in obesity, type 2 diabetes and dyslipidemia. Here, these associations are reviewed with respect to liver metabolism and disease.
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