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白花牛角瓜Calotrpis prcesa(Ait). R. Br.是一种广泛生长于亚洲和非洲热带地区的植物,其不同部位具有不同的生物活性,如蛋白水解、抗微生物、抗生育、驱虫和抗癌等,在传统的印度医学中,应用于治疗嘛风、溃疡、肿瘤,痔疮、腹泻、寄生虫等疾病,还可用于堕胎和解蛇毒。实验材料的制备:自然干燥的白花牛角瓜根的粉末用石油醚和氯仿提取后,真空蒸去氯仿,干燥,得棕黄色氯仿提取物供药理试验用。结果:1.对角叉菜胶所致的大鼠足肿胀的影响:雄性大鼠分别腹腔注射5、10和15mg/kg的白花牛角瓜根提取物,用剂量100mg/kg保泰松作阳性对照药。结果均能显著抑制角又菜胶引起的足肿胀(P<0.001)
Carobrpis prcesa (Ait). R. Br. is a plant widely grown in tropical regions of Asia and Africa. Its different parts have different biological activities, such as proteolysis, anti-microbial, anti-fertility, insect repellency and resistance. Cancer, in traditional Indian medicine, is used to treat diseases such as wind, ulcers, tumors, acne, diarrhea, parasites, etc. It can also be used for abortion and solution of snake venom. Preparation of experimental materials: The powder of the natural dried white calamel melon root was extracted with petroleum ether and chloroform, chloroform was evaporated in vacuo, and dried to give a brown-yellow chloroform extract for pharmacological experiments. Results: 1. Effect of carrageenan-induced foot swelling in rats: Male rats were injected intraperitoneally with 5, 10, and 15 mg/kg of C. mellonella root extract and treated with a dose of 100 mg/kg phenylbutazone. Control medicine. All of the results could significantly inhibit the foot swelling caused by Jiaojiao (P<0.001).