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为了明确减低后负荷对伴有轻一中度主动脉瓣狭窄的心力衰竭患者的效应,作者对11例重度充血性心力衰竭伴主动脉瓣面积减小的患者进行研究,所有患者均经心导管检查以明确瓣膜狭窄的程度。其中3例瓣膜面积减小是由于原发狭窄,另8例为主动脉修补术后狭窄。所有患者都有跨瓣压差,最大为17±3mmHg(平均±标准差);主动脉瓣面积指数为0.7±0.1cm~2/m~2。服用适量的肼苯达嗪(9例)或呱唑嗪(prazosin)(2例)后,心脏指数从2.2±0.1增高到3.3±0.21/min/m~2(P<0.001),每搏容量指
In order to clearly reduce the effect of postload on heart failure patients with mild-to-moderate aortic stenosis, the authors studied 11 patients with severe congestive heart failure with reduced aortic valve area. All patients underwent cardiac catheterization Check to clarify the degree of valvular stenosis. Three cases of valve area reduction was due to primary stenosis, and the other eight cases were aortic stenosis. All patients had transvalvular pressure differences of up to 17 ± 3 mm Hg (mean ± standard deviation) and aortic valve area index of 0.7 ± 0.1 cm 2 / m 2. Cardiac index increased from 2.2 ± 0.1 to 3.3 ± 0.21 / min / m 2 (P <0.001) after taking the appropriate amount of hydralazine (n = 9) or prazosin (n = 2) Means