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目的观察稳心颗粒联合美托洛尔治疗冠心病合并心律失常的临床效果。方法将医院心内科治疗的80例冠心病合并心律失常患者随机分为观察组和对照组,每组40例。对照组采用美托洛尔治疗,观察组采用稳心颗粒联合美托洛尔治疗,2个疗程后比较2组患者的治疗效果、心功能及不良反应。结果观察组总有效率为92.50%,高于对照组的77.50%(P<0.05);观察组室早数、短阵室速数、PR间期、QRS波时限、QTc间期等心电图指标均优于对照组(P<0.05);2组不良反应比较差异无统计学意义(P>0.05)。结论稳心颗粒联合美托洛尔治疗冠心病合并心律失常疗效显著,从多个方面产生抗心律失常作用,且不良反应少,具有积极的临床意义。
Objective To observe the clinical effect of Wenxin granule combined with metoprolol in the treatment of coronary heart disease complicated with arrhythmia. Methods Eighty patients with coronary heart disease and arrhythmia treated by hospital cardiology were randomly divided into observation group and control group, 40 cases in each group. The control group was treated with metoprolol. The observation group was treated with Wenxin Granule combined with metoprolol. The therapeutic effect, cardiac function and adverse reactions of the two groups were compared after two courses of treatment. Results The total effective rate in the observation group was 92.50%, which was significantly higher than that in the control group (77.50%) (P <0.05). All the ECG indexes such as the early number of ventricular tachycardia, the number of ventricular tachycardia, PR interval, QRS wave duration, QTc interval (P <0.05). There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion Wenxin granule combined with Metoprolol is effective in treating coronary heart disease complicated with arrhythmia. It has antiarrhythmic effect in many aspects and has few adverse reactions. It has a positive clinical significance.