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目的观察思密达、葡萄糖酸锌联合应用治疗小儿秋季腹泻的临床疗效。方法将48例秋季腹泻患儿随机分成治疗组和对照组两组,每组各24例。对照组给予纠正脱水、电解质紊乱、抗感染、微生态制剂及肠粘膜保护剂等常规治疗;治疗在此基础上联合应用思密达、葡萄糖酸锌,观察比较两组的疗效。结果研究组的总有效率明显高于对照组,研究组的大便好转时间、止泻时间及退热时间明显短于对照组(P<0.05)。均未见明显不良反应。结论思密达、葡萄糖酸锌联合应用治疗小儿秋季腹泻疗效好,能明显改善患儿的临床症状,值得推广应用于临床。
Objective To observe the clinical effect of combination of Smectite and Zinc Gluconate in the treatment of infantile autumn diarrhea. Methods 48 cases of children with autumnal diarrhea were randomly divided into treatment group and control group, with 24 cases in each group. The control group was given routine treatment of dehydration, electrolyte imbalance, anti-infective, probiotics and intestinal mucosal protective agent. On the basis of the treatment, the combination of Smecta and Zinc Gluconate was used to observe and compare the curative effect of the two groups. Results The total effective rate of the study group was significantly higher than that of the control group. The stool improvement time, antidiarrheal time and antipyretic time in the study group were significantly shorter than those in the control group (P <0.05). No obvious adverse reactions were seen. Conclusion Smecta and zinc gluconate combined with the treatment of children with autumn diarrhea good effect, can significantly improve the clinical symptoms of children, it is worth promoting the clinical application.