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目的 探讨尘螨过敏与哮喘之间的关系。方法 测定不同年龄哮喘患儿和正常儿童的血清IgE水平以及尘螨皮试反应。结果 ①婴幼儿哮喘屋尘螨皮试阳性率较低 (34% ) ,在儿童哮喘则明显上升达 70 % (P <0 0 0 1) ;②各年龄组皮试阳性的哮喘患儿血清IgE水平均明显高于皮试阴性哮喘患儿 (P <0 0 0 1) ;③婴幼儿期血清IgE迅速升高 ,尤其婴幼儿哮喘上升幅度更加明显 ;进入儿童期后上升幅度明显放慢。结论 屋尘螨过敏是婴幼儿哮喘发展成儿童哮喘的重要因素之一 ;血清IgE升高与屋尘螨皮试表达有一定的关系 ,但它的表现明显早于屋尘螨皮试的表达 ;为此动态测定婴幼儿哮喘血清IgE水平有助于判断婴幼儿哮喘的预后
Objective To explore the relationship between dust mite allergy and asthma. Methods The levels of IgE in serum and the skin test of dust mites were determined in asthmatic children and normal children of different ages. Results ① The positive rate of house dust mite skin test in infants and young children was low (34%) and significantly increased in children with asthma (70%) (P <0.01). ② Serum IgE (P <0.01). ③ Serum IgE increased rapidly in infancy, especially in infants and young children. The increase rate of asthma in infants and young children was more obvious. The increase rate of childhood asthma was obviously slowed down. Conclusions The house dust mite allergy is one of the important factors in the development of asthma in infants and young children. Asthmatic serum IgE has some relationship with the expression of house dust mite, but its performance is obviously earlier than the house dust mite skin test. Therefore, the dynamic determination of serum IgE levels in infants and young children with asthma help to determine the prognosis of infant asthma