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幽门螺杆菌（Ｈｐ）相关性十二指肠球部溃疡（ＤＵ）患者８３例，随机分为２组，口服不同剂量的奥美拉唑、克拉霉素和羟氨苄青霉素１０日。疗程结束后４周复查Ｈｐ、ＤＵ愈合和观察组织炎症细胞浸润情况。结果：２组间的Ｈｐ根除率分别为８８．６％和９２．３％；溃疡愈合总有效率为９７．７％和１００％，均无统计学差异。而Ｈｐ根除后胃窦粘膜组织炎症细胞浸润程度和活动度，均比治疗前明显减轻。结果表明：奥美拉唑、克拉霉素和羟氨苄青霉素低剂量三联１０日疗法，是较理想的治疗Ｈｐ相关性ＤＵ的方案
Eighty-three patients with Helicobacter pylori (Hp) -related duodenal ulcer (DU) were randomly divided into two groups. Omeprazole, clarithromycin and amoxicillin were orally administered at different doses for 10 days. Four weeks after the end of the course of treatment, Hp was observed and the DU healed and the infiltration of inflammatory cells in the tissue was observed. Results: The Hp eradication rates of the two groups were 88.6% and 92.3%, respectively. The total effective rates of ulcer healing were 97.7% and 100%, respectively, with no significant difference. Hp eradication gastric mucosa inflammatory cell infiltration and activity were significantly reduced than before treatment. The results showed that omeprazole, clarithromycin and amoxicillin low-dose triple therapy on the 10th, is more ideal for the treatment of Hp-related DU program