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随着近十余年对埃及血吸虫流行病学数学模型论文的发表,阐明了年龄-感染度关系所反映的获得性免疫力,寄生虫-宿主动力学问题又引起了兴趣。宿主的(寄生)虫负荷既对感染力亦对虫的死亡率的影响,可视为密度依赖效应,自然获得性免疫即是密度依赖的特例。两种特别有意义的年龄-感染度关系的现象是涉及感染度的高峰年龄和高度感染者的相对不均匀性。可以预期,获得性免疫将引出两种情况:(一)感染度高峰年龄越趋于低龄化,则人群中高度感染者越多;(二)在社区中人与人之间重度感染者的分布随年
With the publication of the essay on the mathematical model of schistosomiasis epidemiology for nearly a decade, the acquired immunity reflected by the age-infection relationship was elicited and the parasitic host-host kinetics was of interest. Host (parasitic) insect burden on both infectivity and mortality of insects can be considered as density-dependent effects of natural acquired immunity is a special case of density-dependent. The phenomenon of two particularly significant age-prevalence relationships is the peak age involved in infectivity and the relative inhomogeneity of highly infected individuals. It can be expected that access to immunity will lead to two situations: (i) the age at peak infection tends to be younger, the more highly infected are in the population; (ii) the distribution of persons with severe infections among people in the community Year after year