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目的:研究在高血压性脑出血的早期运用尼莫地平进行治疗的临床效果。方法:把在11～12年间在我院接受高血压治疗的患者选做分析对象,将80例患者各分为40例对照组和40例观察组。观察组不仅要进行平时的治疗工作,还应该在早期应用尼莫地平做联合治疗,而对照组只做常规的治疗。这两组在接受治疗之前都应该做神经缺损的评定和后头颅CT情况的检测,随后在一个月中定期将两组的治疗工作做对比研究。结果:在这一个月内定期的对比观察中发现对照组的神经功能恢复情况比对照组差很多,彼此的差异符合统计学意义。而血肿周围低密度区和血肿块的体积大小差异性对比上,观察组比对照组更具差异性,两组的对比符合统计学意义。因此在这两组的疗效对比观察中,对照组较观察组的差异性更小,(P<0.05)具有统计学意义。结论:在高血压发病的早期对患者使用尼莫地平来进行治疗更有助于神经缺损的改善工作,并且还能遏制血块的肿大,将脑水肿的症状减轻。
Objective: To study the clinical effect of nimodipine in the early stage of hypertensive intracerebral hemorrhage. Methods: The patients who underwent hypertension treatment in our hospital during 11 ~ 12 years were selected as the analysis object, 80 patients were divided into 40 control groups and 40 observation groups. The observation group not only to carry out the usual treatment, but also should be combined with early treatment of nimodipine, while the control group only routine treatment. Both groups should be assessed for neurological deficits and CT examination of the posterior cranium before treatment, followed by a regular comparison of the two groups over the course of a month. Results: In the regular comparative observation during this month, we found that the recovery of neurological function of the control group was much worse than that of the control group, and the differences between the two groups were statistically significant. The hematoma around the low-density area and the size of the contrast hematoma volume, the observation group was more different than the control group, the two groups were statistically significant. Therefore, in the comparison of the curative effect between the two groups, the difference between the control group and the observation group is smaller (P <0.05). CONCLUSIONS: Nimodipine treatment in patients with early onset of hypertension contributes more to the improvement of neurological deficits and also to the suppression of swelling in the clot to alleviate the symptoms of cerebral edema.