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[目的]了解乐山市美沙酮门诊吸毒人群HIV、HCV、梅毒和HSV-2感染状况。[方法]采集乐山市3个区市(县)的美沙酮门诊618名吸毒人员的静脉血进行HIV、HCV、梅毒以及HSV-2血清抗体检测,并对检测结果进行分析。[结果]618名吸毒人员HIV抗体阳性率为10.84%,HCV抗体阳性率为71.84%,梅毒抗体阳性率为4.85%;3个美沙酮门诊吸毒人员HIV抗体阳性率以及HCV抗体阳性率差异有统计学意义(χ2=9.43,P=0.01;χ2=29.75,P=0.00);各年龄段间HCV抗体阳性率差异有统计学意义(χ2=5.23,P=0.00);HIV/HCV合并感染率为5.18%、HIV/HCV/梅毒合并感染率为0.16%、HCV/梅毒合并感染率为3.56%。67例艾滋病感染者HSV-2抗体阳性率为61.19%,HIV/HCV/梅毒/HSV-2疱疹合并感染率为1.49%,HIV/HCV/HSV-2疱疹合并感染率为52.24%。[结论]乐山市美沙酮门诊吸毒人群中HIV、HCV、梅毒以及HSV-2感染率较高,合并感染现象严重,应积极开展健康教育并采取针对性的干预措施。
[Objective] To understand the HIV, HCV, syphilis and HSV-2 infection among methadone outpatients in Leshan City. [Methods] The venous blood of 618 drug addicts from methadone clinics in 3 districts and counties of Leshan was collected for the detection of HIV, HCV, syphilis and HSV-2 serum antibodies, and the test results were analyzed. [Results] The positive rate of HIV antibody in 618 drug addicts was 10.84%, the positive rate of HCV antibody was 71.84%, and the positive rate of syphilis antibody was 4.85%. The positive rate of HIV antibody and the positive rate of HCV antibody in three methadone outpatients were statistically different (Χ2 = 9.43, P = 0.01; χ2 = 29.75, P = 0.00). There was significant difference in the positive rate of HCV antibody among all age groups (χ2 = 5.23, P = 0.00) %, HIV / HCV / syphilis combined infection rate was 0.16%, HCV / syphilis combined infection rate was 3.56%. The positive rate of HSV-2 antibody in 67 HIV-infected patients was 61.19%, the combined infection rate of HIV / HCV / syphilis / HSV-2 herpes was 1.49%, and the combined infection rate of HIV / HCV / HSV-2 herpes was 52.24%. [Conclusion] The prevalence of HIV, HCV, syphilis and HSV-2 among drug addicts in methamphetamine outpatient population in Leshan City is high, and the infection rate is serious. Health education should be actively carried out and targeted interventions should be taken.