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目的通过对深圳福田区符合艾滋病免费抗病毒治疗患者的流行病学资料分析,以探讨对治疗依从性可能存在的影响因素。方法收集福田区所有需要接受抗病毒治疗艾滋病患者基本情况及接受治疗后临床资料分析其流行病学特征。结果福田区累计174名患者需接受治疗,目前134人在治,治疗覆盖率77.0%。以中年为主,男女性别比2.3:1,初中及以下文化程度占63.2%,感染途径主要为性传播途径(占87.4%)。开始治疗前无明显临床症状的人仅占12.1%,84.5%的患者CD4+T淋巴细胞计数≤200个/μl;进入治疗中35.1%会出现药物副反应,9.7%出现机会性感染或者新疾病。结论艾滋病感染者需探讨更有效的早发现及治疗的模式。
Objective To analyze the epidemiological data of patients with AIDS-free antiviral therapy in Futian District, Shenzhen, so as to explore the possible influencing factors of compliance with treatment. Methods The basic situation of AIDS patients receiving antiviral therapy in Futian District was collected and their epidemiological characteristics were analyzed after clinical treatment. Results A total of 174 patients in Futian District needed treatment. At present, 134 patients are under treatment and the treatment coverage rate is 77.0%. Middle-aged, male to female ratio of 2.3: 1, 63.2% of junior high school education and below, the main route of transmission for sexual transmission (accounting for 87.4%). Only 12.1% of patients had no clinical symptoms before treatment, CD4 + T lymphocyte count was less than or equal to 200 in 84.5%, side effects were found in 35.1%, 9.7% of opportunistic infections or new diseases . Conclusion HIV-infected patients need to explore more effective patterns of early detection and treatment.