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目的 了解白血病输血的合理应用、输血的临床效果及副作用 ,指导合理输血。方法 以《献血法》实施前后分阶段总结近年经输血治疗的 5 2例白血病 ,了解其输血的理由 ,判断其输血的合理性 ,比较不同血液成分的疗效及副作用。结果 1995～ 1997年 33例白血病共输血 36 6例次 ,不必要输血 16例次 (4 4% ) ,输血成分不适当的达 189例次(5 1 6 % ) ,主要为全血的使用不当 ;《献血法》实施后 1998～ 1999年 19例白血病输血 2 2 0例次 ,全血仅 4例次 (1 8% ) ,无不必要输血。成分输血的疗效明显优于全血输注 ,输血副反应主要见于全血输注。结论 小儿白血病确需大量、多次输血 ,但应该强调合理应用成分输血 ,通过更新输血理论及加强输血管理能合理调控成分输血 ,节省血液资源 ,避免血液浪费 ,减轻患者的经济负担 ,提高输血疗效 ,减少输血副作用
Objective To understand the rational application of blood transfusion in leukemia, the clinical effect and side effects of blood transfusion to guide rational blood transfusion. Methods To summarize 52 cases of leukemia treated by blood transfusion in phases before and after the implementation of “blood donation method”, understand the reason of blood transfusion, judge the rationality of blood transfusion and compare the curative effects and side effects of different blood components. Results A total of 366 cases of 33 cases of leukemia were transfused in 1995-1997, 16 cases were unnecessary transfusion (44%) and 189 cases (5.16%) were inappropriately transfused, which was mainly due to improper use of whole blood In the period from 1998 to 1999, 19 cases of leukemia transfused 220 cases and only 4 cases of whole blood (18%) after the implementation of the “Blood Donation Law”. No blood transfusion was necessary. The efficacy of transfusion of blood components was significantly better than that of whole blood transfusion. Transfusion reactions were mainly found in whole blood transfusion. Conclusion Pediatric leukemia requires a large number of blood transfusions. However, it is necessary to emphasize the rational use of component blood transfusion. Blood transfusion can be reasonably controlled by updating the theory of blood transfusion and strengthening blood transfusion management to save blood resources, avoid blood wastage, reduce patients’ financial burden and improve blood transfusion efficacy , Reduce the side effects of blood transfusion