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自身外周血(PB)干细胞移植可促进多种恶性疾病在大剂量治疗后骨髓(BM)功能的恢复。本文报道40例难治性淋巴瘤伴 BM 病变病人用大剂量治疗和自身 PB 干细胞移植的结果。病人和方法病人年龄中位数34(11～57)岁,男28、女12例。均对常规治疗不起反应,没有与淋巴瘤无关的主要器官损伤,在血流中无淋巴瘤细胞存在.所有患者除1例由于采集的 BM 在冷藏过程中出现差错而被破坏外,均有各种各样的 BM 异常。40例中24例为何杰金病(HD)、16例为非何杰金淋巴瘤(NHL).
Self-peripheral blood (PB) stem cell transplantation can promote the recovery of the function of bone marrow (BM) in a variety of malignant diseases after high-dose treatment. This article reports the results of 40 patients with refractory lymphoma with BM disease treated with high-dose and their own PB stem cell transplantation results. Patients and Methods The median age of patients was 34 (11-57) years old, 28 males and 12 females. All failed to respond to conventional therapy, no major organ damage unrelated to lymphomas, and no presence of lymphoma cells in the bloodstream.1 All patients except one were destroyed due to errors in the collected BM during refrigeration Various BM abnormalities. Of the 40 patients, 24 were Hodgkin’s disease (HD) and 16 were non-Hodgkin lymphoma (NHL).