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目的了解孝感市中心医院1个月～5岁之间腹泻患儿轮状病毒(RV)的感染情况。方法采集腹泻患儿的新鲜粪便标本,采用A群轮状病毒诊断试剂盒,对该院2008～2010年住院部儿科及感染腹泻患儿的粪便标本进行A群轮状病毒的检测。结果在1813例腹泻的患儿粪便中检查536例RV阳性标本,阳性率为29.6%;其中秋季779例,检出RV阳性标本320例,占41.2%;冬季544例,检出RV阳性标本174例,占32%;年龄段在0～0.5岁婴幼儿感染率达到26.2%;0.5～2岁婴幼儿感染率为46.7%,随着年龄增大,轮状病毒感染率随之降低。结论 RV感染是导致婴幼儿腹泻的主要原因之一,以6个月～2岁组为A群轮状病毒的高发年龄组,每年秋冬季为感染高发期。从粪便中检测RV抗原,对婴幼儿感染性与病毒性腹泻的早期快速鉴别诊断提供了可靠依据。
Objective To understand the infection of rotavirus (RV) in children with diarrhea between 1 month and 5 years old in Xiaogan Central Hospital. Methods Fresh stool samples of children with diarrhea were collected. A group A rotavirus diagnostic kit was used to detect group A rotavirus in stool specimens of pediatric patients and children with diarrhea admitted to the hospital from 2008 to 2010. Results 536 RV positive specimens were detected in the faeces of 1813 children with diarrhea, the positive rate was 29.6%. Among them, 779 were positive in autumn, 320 were positive for RV, accounting for 41.2%; in 544 in winter, RV positive specimens were detected Cases, accounting for 32%. The infection rate of infants and young children aged 0-0.5 years reached 26.2%. The infection rate of infants aged 0.5-2 years was 46.7%. As the age increased, the infection rate of rotavirus decreased. Conclusions RV infection is one of the major causes of diarrhea in infants and young children. It takes 6 months to 2 years as the high incidence group A rotavirus, and autumn and winter each year is the period of high infection. The detection of RV antigen from the stool provides a reliable basis for the early rapid differential diagnosis of infantile infection and viral diarrhea.