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用液中干燥法制备了氨苄青霉素钠-乙基纤维素微囊,并用荧光分光光度法测定该微囊在家兔体内的血药浓度。结果表明,家兔口服微囊与药粉相比,其相对生物利用度为185.6%。
Ampicillin sodium-ethylcellulose microcapsules were prepared by liquid-drying method, and the plasma concentration of the microcapsules in rabbits was determined by fluorescence spectrophotometry. The results showed that the relative bioavailability of rabbits oral microencapsulated drug powder was 185.6%.