多发性骨髓瘤的急性肾功能衰竭

• 作 者: 叶德富
• 出 处: 福建医大
• 发表日期: 1977年02期
• 关键词: 急性肾功能衰竭 多发性骨髓瘤 肌酐浓度 肾功能损害 血清尿素氮 高钙血症 血清蛋白 烷化剂 肾组织学 间质水肿

肾功能竭常为多发性骨髓瘤的不良征兆,有时近半数病例可以发生。本文在187例复习中,发现80例伴有肾功能衰竭,血清尿素氮(SUN)>40毫克％及/或血清肌酐>2毫克％。66例为慢性肾功能衰竭,急性者为14例(占7％)。 14例急性肾功能衰竭的平均年龄为64岁,男女各占7例。肾功能损害表现为;(1)SUN及肌酐浓度增高(SUN由85～201毫克％;肌酐从5.6～14毫克％)。(2)血清及尿蛋白变异:13例血清蛋白异常;10例尿本一周氏蛋白阳性;全部病例均有蛋白尿。(3)

Renal function is often a symptom of multiple myeloma, sometimes in nearly half of cases. In this review of 187 cases, 80 were found to have renal failure with a serum creatinine (NOS)> 40 mg% and / or serum creatinine> 2 mg%. 66 cases of chronic renal failure, acute cases were 14 cases (7%). The average age of 14 patients with acute renal failure was 64 years old, with 7 men and women each. Renal dysfunction manifested; (1) SUN and creatinine concentrations increased (SUN from 85 to 201 mg%; creatinine from 5.6 to 14 mg%). (2) Serum and urinary protein variation: 13 cases of abnormal serum protein; 10 cases of urine week positive protein; all cases have proteinuria. (3)