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目的观察盐酸氨溴索注射液辅助治疗支气管肺炎的疗效及安全性。方法将66例支气管肺炎患儿采用随机对照的方法分为两组,治疗组(33例)和对照组(33例),两组均同时给予抗感染、抗病毒及对症等综合常规治疗,治疗组在综合治疗基础上加用盐酸氨溴索每次7.5mg静脉滴注,2次/d,疗程5～7d,观察比较两组患儿症状、体征消失时间及不良反应。结果治疗组显效率(93.9%)明显高于对照组(78.7%)(P<0.05)、治疗组咳嗽、气急消失天数及肺部啰音消失时间,住院天数均较对照组明显缩短。结论盐酸氨溴索注射液辅助治疗支气管肺炎,可以迅速缓解症状,缩短住院天数,提高治愈率。值得临床推广使用。
Objective To observe the efficacy and safety of ambroxol hydrochloride injection in the treatment of bronchial pneumonia. Methods Sixty-six children with bronchopneumonia were randomly divided into two groups: treatment group (33 cases) and control group (33 cases). Both groups were given general anti-infection, anti-virus and symptomatic treatment, On the basis of comprehensive treatment, the patients were treated with ambroxol hydrochloride 7.5 mg intravenously twice daily for 5-7 days. The symptoms and signs disappeared and the adverse reactions were observed and compared in both groups. Results The markedly effective rate (93.9%) in the treatment group was significantly higher than that in the control group (78.7%) (P <0.05). The cough, the number of disappearance of shortness of breath, the disappearance of pulmonary rales and the length of hospital stay in the treatment group were significantly shorter than those in the control group. Conclusion Ambroxol hydrochloride injection in the treatment of bronchial pneumonia, can quickly relieve symptoms, shorten the length of stay, and improve the cure rate. It is worth to promote clinical use.