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烧伤后的超高代谢是烧伤应激反应的一部分。以往有关超高代谢的研究很少注意垂体甲状腺系统的变化。本文观察超高代谢的甲状腺动力学,探讨了超高代谢与甲状腺功能之间的关系。结果,烧伤面积与甲状腺功能之间有密切的关系。烧伤面积越大,血清T_3 T_4值下降越明显,经过治疗,随着病情的恢复,血清T_3、T_4逐渐回升到正常水平。休克时间的长短与血清T_3、T_4亦密切相关,严重病例血清T_3 T_4逐渐下降,死亡前出现典型的甲状腺机能减退症的变化。经抢救渡过休克的病例血清T_3、T_4接近正常值的下限,并血清TSH显著上升。上述结果表明,烧伤超高代谢与垂体-甲状腺轴功能密切相关。
Hyperbolic metabolism after burn is part of the burn stress response. Previous studies of hypermetabolism paid little attention to the changes of pituitary thyroid system. This article observes thyroid dynamics of hypermetabolism and explores the relationship between hypermetabolism and thyroid function. As a result, there is a close relationship between burn area and thyroid function. The larger burn area, serum T_3 T_4 value decreased significantly, after treatment, with the recovery of the disease, serum T_3, T_4 gradually returned to normal levels. The duration of shock time was also closely related to serum T_3 and T_4, serum T_3 T_4 decreased gradually in severe cases, and typical hypothyroidism occurred before death. Serum T_3 and T_4 in the cases of rescuing through shock approached the lower limit of normal and serum TSH increased significantly. The above results show that the hypermetabolism of burn is closely related to the function of pituitary-thyroid axis.