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6正性肌力药物的相互作用(地高辛)我们已知奎尼丁与地高辛的相互作用(表7)。奎尼丁大约可使血液中地高辛浓度增加1倍,因此减少了药物在肾脏和肾外的清除。其机制是奎尼丁抑制了地高辛跨膜转运体P-糖蛋白。奎宁也用于肌肉痉挛。维拉帕米与地高辛的相互作用明显;地高辛浓度可因此
Interaction of Inotropes (Digoxin) We have known the interaction of quinidine with digoxin (Table 7). Quinidine can double the concentration of digoxin in the blood, thereby reducing the clearance of drugs in the kidneys and kidneys. The mechanism is that quinidine inhibits digoxin transmembrane transporter P-glycoprotein. Quinine is also used for muscle spasms. The interaction between verapamil and digoxin is significant; the concentration of digoxin can therefore be