论文部分内容阅读
目的:探讨低管电压(110 kVp)与低对比剂量(1.0 mL/kg)在肝脏CT增强扫描中的可行性。方法:116例行肝脏CT增强扫描,且BMI<25kg/m~2的患者,随机分成A、B两组进行研究,每组58例。A组:管电压110 kVp,对比剂碘帕醇(300 mgI/mL),对比剂量(1.0 mL/kg),采用正弦迭代重建(SAFIRE)。B组:管电压130 kVp,对比剂碘帕醇(300 mgI/mL),对比剂量(1.2 mL/kg),采用滤波反投影重建算法(FBP)。测量动脉期腹主动脉CT值、肝门脉期门静脉CT值及增强扫描3期(动脉期、门脉期、延迟期)的肝右叶肝实质CT值;计算两组图像的肝动脉期对比噪声比(CNR)、信噪比(SNR)及总有效辐射剂量ED;并对两组图像进行评分,进行统计学分析。结果:A组和B组CNR、SNR差异无统计学意义(P>0.05);两组分别在增强扫描3期测得肝右叶肝实质CT值及动脉期腹主动脉CT值差异亦无统计学意义(P>0.05);肝门脉期A组的门静脉CT值低于B组统计学差异有意义(P<0.05)。A组的3期总有效辐射剂量(ED)(9.88±3.56)mSv低于B组(13.91±4.71)mSv,统计学差异有显著意义(P<0.001);A组比B组的对比剂量减少17%。结论:128层MSCT在肝脏增强CT扫描中,应用低管电压(110 kVp)和低对比剂量(1.0 mL/kg),联合迭代重建技术(SAFIRE),可以得到较好的图像质量,同时降低辐射剂量及人体碘摄入量。
Objective: To explore the feasibility of low voltage (110 kVp) and low contrast dose (1.0 mL / kg) in enhanced CT scanning in liver. Methods: One hundred and sixty-six patients in each group were randomly divided into A and B groups, and 116 patients underwent enhanced CT scan of liver with BMI <25 kg / m ~ 2. Group A: The tube voltage was 110 kVp, contrast agent iopamidol (300 mgI / mL), and contrast dose (1.0 mL / kg), using sinusoidal iterative reconstruction (SAFIRE). Group B: Filtered back projection reconstruction (FBP) was performed with a tube voltage of 130 kVp, contrast agent iopamidol (300 mgI / mL) and a contrast dose of 1.2 mL / kg. The CT value of the abdominal aorta in the arterial phase, the CT value of the portal vein in the portal phase and the CT value of the liver parenchyma in the third phase (arterial phase, portal phase, and delayed phase) were measured. The hepatic arterial phase Contrast to noise ratio (CNR), signal to noise ratio (SNR) and total effective radiation dose ED; and the two groups of images were scored for statistical analysis. Results: There was no significant difference in CNR and SNR between group A and group B (P> 0.05). There was no statistical difference in CT value of right hepatic lobe and arterial phase CT between the two groups (P> 0.05). The CT value of portal vein in group A was lower than that in group B (P <0.05). The total effective radiation dose (ED) in group A (9.88 ± 3.56) mSv was lower than that in group B (13.91 ± 4.71) mSv, the difference was statistically significant (P <0.001) 17%. Conclusions: The 128-slice MSCT can achieve better image quality and reduce the radiation dose in liver enhanced CT scan with low voltage (110 kVp) and low contrast dose (1.0 mL / kg) in combination with iterative reconstruction technique (SAFIRE) Dose and body iodine intake.