TBL1XR1 induces cell proliferation and inhibit cell apoptosis by the PI3K/AKT pathway in pancreatic

• 作 者: Jian-Feng Gu Wei Fu Hai-Xin Qi
• 机 构: DepartmentofGeneralSurgery,DepartmentofOncology,DepartmentofGeneralSurgery
• 出 处: 世界胃肠病学杂志:英文版
• 发表日期: 2020年25期
• 关键词: Pancreatic ductal adenocarcinoma TBL1XR1 PROLIFERATION PI3K/AKT pathway

BACKGROUND Pancreatic ductal adenocarcinoma(PDAC) is one of the deadliest solid tumors. Identification of diagnostic and therapeutic biomarkers for PDAC is urgently needed. Transducin(β)-like 1 X-linked receptor 1(TBL1 XR1) has been linked to the progress