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目的了解四川省合江县健康人群流脑脑膜炎奈瑟氏菌(Nm)带菌情况和抗体水平,为制定科学防控对策提供依据。方法在流脑流行前期在合江县采集健康人群咽拭子并进行脑膜炎奈瑟氏菌(Nm)菌株分离培养,采集健康人群血液进行抗体水平检测。结果健康人群带菌率为2.83%,健康人群A群流脑血清抗体阳性率较高(63.33%),其余3群阳性率较低(12.5~15.5%),健康人群对C、Y和W135群流脑保护率相当低(2%~3%)。结论加强3岁以下儿童的A群流脑菌苗的接种工作,开展15岁以下儿童的A+C+Y+W135四价流脑菌苗接种工作。
Objective To understand the prevalence and antibody levels of Neisseria meningitidis (Nm) in healthy population in Hejiang County, Sichuan Province, and to provide basis for making scientific prevention and control measures. Methods Throat swabs were collected from healthy people in Hejiang County in the early stage of meningococcal epidemic. Isolates of Neisseria meningitidis (Nm) strains were isolated and cultured. Blood samples were obtained from healthy people for antibody detection. Results The positive rate of seropositive antibody in group A was higher (63.33%) than that in healthy group (2.83%), while the positive rate was lower in healthy group (12.5-15.5%). Brain protection rate is very low (2% to 3%). Conclusions Intensive vaccination of group A meningococcal vaccine in children under three years of age is carried out and vaccination of A + C + Y + W135 tetravalent meningococcal vaccine is carried out in children under 15 years of age.