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目的探讨氦氧混合气最大呼气流量 -容积曲线在支气管哮喘诊断中的应用价值。方法测定 2 5例缓解期支气管哮喘患者呼吸氦氧混合气前后的最大呼气流量 -容积曲线 (MEVC) ,此组称为支气管哮喘组并设对照组进行比较。结果两组 MEVCair结果除用力肺活量 (FVC)外、MEVCHe- O2 结果全部有显著性差异 (P<0 .0 5 ) ;两组 MEVCHe- O2 结果皆较 MEVCair结果有不同的增加 ,但增加百分率除ΔFVC外皆无显著性差异 (P>0 .0 5 ) ;支喘组呼吸氦氧混合气前后 FVC、一秒用力呼气容积 (FEV1 )、最大呼气流量 (PEF)虽有显著性差异 (P<0 .0 5 ) ,但主要判定大、小气道阻塞与否的 Vmax75、Vmax50 和 Vmax2 5皆无显著性差异 (P>0 .0 5 )。结论 MEVCHe- O2 对支气管哮喘无特殊的诊断价值 ,其作用与 MEVCairr无明显差异。
Objective To investigate the value of the maximal expiratory flow volume-volume curve of helium-oxygen mixture in the diagnosis of bronchial asthma. Methods The maximum expiratory flow volume-volume curve (MEVC) before and after breathing Helic-Oxygen mixed gas in 25 patients with remission bronchial asthma was measured. The group was called bronchial asthma group and the control group was compared. Results The results of MEVCair between two groups showed significant differences (all P <0.05) except for forced vital capacity (FVC). The results of MEVCHe-O2 in both groups differed from those of MEVCair, but the percentages of addition (P> 0.05). There were significant differences in FVC, FEV1 and PEF before and after the treatment of bronchial asthma in the asthma group <0.05). However, there was no significant difference in Vmax75, Vmax50 and Vmax2 5 between the major and minor airway obstruction (P> 0.05). Conclusion MEVCHe-O2 has no special diagnostic value for bronchial asthma, and its effect has no significant difference with MEVCairr.