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目的 :分析 2型DM患者微血管病变 (DMIP)的患病率及其临床危险因素。方法 :对 1993年 3月 1998年 7月在我科住院或门诊的 12 17例 2型DM进行回顾性调查。按有无糖尿病视网膜病变 (DRP)和糖尿病肾病 (DNP)分组 ,分别统计其患病率 ,用logistic多元回归分析微血管病变的相关因素和危险因素。 结果 :DRP的总患病率为 2 4 9% ,其中背景性视网膜病变和增殖性视网膜病变分别为 2 1 0 %和 3 9% ;DNP的总患病率为19 3% ,其中微量白蛋白尿 ,临床蛋白尿和肾功能不全分别为 10 0 % ,5 9%和 3 4%。Logistic回归结果显示 ,DM病程 (COUR)、平均动脉压 (MBP)、HbA1c、糖尿病神经病变 (DUP)和DRP是DNP的独立危险因素 ,COUR、MBP、HbA1c、TG、CH、DUP和DRP和DNP是独立危险因素。结论 :DRP和DNP的患病率分别为 2 4 9%和19 3%。COUR、MBP、HbA1c、DUP和DNP是DRP独立危险因素 ,DM病程 ,MBP、HbA1c、CH、TG、DUP和DRP是DNP的独立危险因素
Objective: To analyze the prevalence and clinical risk factors of microvascular disease (DMIP) in type 2 DM patients. Methods: A retrospective survey was performed on 12 17 type 2 DM patients who were hospitalized or outpatient in our department from March 1993 to July 1998. The prevalence of diabetic retinopathy (DRP) and diabetic nephropathy (DNP) were divided into groups according to the prevalence. The related factors and risk factors of microangiopathy were analyzed by logistic multiple regression analysis. Results: The overall prevalence of DRP was 24.9%, of which the background retinopathy and proliferative retinopathy were 21.0% and 39% respectively. The overall prevalence of DNP was 19.3%, in which the microalbumin Urine, clinical proteinuria, and renal insufficiency were 10 0%, 59%, and 34%, respectively. Logistic regression showed that COUR, MBP, HbA1c, diabetic neuropathy (DUP) and DRP were independent risk factors of DNP. COUR, MBP, HbA1c, TG, CH, DUP and DRP and DNP Is an independent risk factor. Conclusions: The prevalence rates of DRP and DNP were 24.9% and 19.3%, respectively. COUR, MBP, HbA1c, DUP and DNP are independent risk factors of DRP. DM duration, MBP, HbA1c, CH, TG, DUP and DRP are independent risk factors of DNP