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目的分析广安市2009-2011年疑似预防接种异常反应(AEFI)的发生特征,评价AEFI监测系统运转情况。方法采用描述流行病学对2009-2011年广安市AEFI病例相关指标进行分析。结果 3年间共报告AEFI40例,其中一般反应19例,异常反应17例,其他4例。临床诊断以发热、红肿、硬结较多,占总数的63.16%。年龄以2岁以内发生最多,占45%。报告发生反应的疫苗品种有16种,最多涉及的疫苗主要为麻疹疫苗10例(25%)。AEFI及时报告率92.5%,及时调查率为90.48%,3日内调查表报告率为100%。结论广安市AEFI监测系统运转良好,AEFI以一般反应为主。要加强预防接种人员规范化操作,严格掌握禁忌证并做好预检筛查,从而减少预防接种后不良事件的发生。
Objective To analyze the occurrence characteristics of suspected AEFI during 2009-2011 in Guang’an and evaluate the operation of AEFI monitoring system. Methods Descriptive epidemiology was used to analyze the related indicators of AEFI cases in Guang’an from 2009 to 2011. Results AEFI was reported in 40 cases over the 3 years, of which 19 cases were general reaction, 17 cases were abnormal reaction and the other 4 cases. Clinical diagnosis of fever, swelling, induration more, accounting for 63.16% of the total. Age occurs up to 2 years old, accounting for 45%. There were 16 vaccine types reported in the report, and the largest number of vaccines were measles vaccine in 10 (25%). AEFI timely reporting rate of 92.5%, timely investigation rate of 90.48%, 3 days survey report was 100%. Conclusion The AEFI monitoring system in Guang’an is working well. AEFI is mainly based on general response. To strengthen the standardized operation of vaccination personnel, strict control of contraindications and do pre-screening screening, thereby reducing the incidence of adverse events after vaccination.