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目的观察无创正压通气治疗新生儿肺炎合并呼吸衰竭的效果。方法选取80例重症肺炎合并呼吸衰竭的患儿为研究对象,按照治疗方法的不同分为观察组50例和对照组30例,对照组采用头罩吸氧治疗,观察组采用无创正压通气治疗,比较2组的治疗效果。结果观察组总有效率为84.0%高于对照组的66.7%(P<0.05)。2组治疗后Pa O2、Sa O2较治疗前升高,Pa CO2较治疗前降低(P<0.05);且观察组治疗1h后Pa O2、Sa O2高于对照组,Pa CO2低于对照组(P<0.05)。p H均未见明显改变。观察组患儿中转有创通气7例(14.0%)。对照组中转10例(33.3%),观察组低于对照组(P<0.05)。观察组住院时间为(14.6±3.5)d短于对照组的(16.2±3.8)d,差异均有统计意义(P<0.05)。结论无创正压通气是治疗新生儿肺炎合并呼吸衰竭的有效方法,可迅速改善患儿的缺氧状态。
Objective To observe the effect of noninvasive positive pressure ventilation on neonatal pneumonia with respiratory failure. Methods 80 cases of severe pneumonia with respiratory failure in children as the research object, according to the different treatment methods were divided into observation group of 50 cases and control group of 30 cases, the control group using head mask oxygen therapy, the observation group using non-invasive positive pressure ventilation , Compare the treatment effect of 2 groups. Results The total effective rate in the observation group was 84.0% higher than that in the control group (66.7%, P <0.05). PaO2 and SaO2 in both groups were higher than those before treatment, PaO2 decreased compared with that before treatment (P <0.05); PaO2 and SaO2 in observation group were higher than those in control group P <0.05). p H had no significant change. In the observation group, 7 children (14.0%) had invasive ventilation. Control group, 10 cases (33.3%), the observation group was lower than the control group (P <0.05). The length of stay in the observation group was (14.6 ± 3.5) d shorter than that in the control group (16.2 ± 3.8) d, the difference was statistically significant (P <0.05). Conclusion Noninvasive positive pressure ventilation is an effective treatment for neonatal pneumonia complicated with respiratory failure, which can rapidly improve the hypoxic state of children.