论文部分内容阅读
随着头孢菌素类抗生素的临床应用日益广泛,近年发生过敏反应的病例也屡有报道。头孢类抗生素的过敏反应主要有皮疹、荨麻疹、血清病样反应、药物热、血管神经性水肿以及过敏性休克等,过敏性休克的症状类似青霉素的休克反应,但致命的过敏反应较罕见。头孢菌素类过敏者绝大多数(接近全部)对青霉素类过敏;而青霉素过敏者中约有10％对头孢菌素类也可引起过敏反应,儿童低于5％,因此需要警惕。在临床广泛使用情况下,认真做好过敏反应试验,是很有必要的。 鉴于头孢类抗生素与青霉素之间存在不完全的交叉过敏反应,在应用头孢
With the increasingly widespread clinical application of cephalosporin antibiotics, cases of allergic reactions have been reported in recent years. Cephalosporin allergy mainly rash, urticaria, serum disease-like response, drug fever, angioneurotic edema and anaphylactic shock, the symptoms of anaphylactic shock similar to penicillin shock response, but a rare fatal allergic reactions. Most (nearly all) cephalosporins are allergic to penicillins; while about 10% of penicillins are allergic to cephalosporins, with children under 5%, so beware. In the case of widespread clinical use, it is necessary to conscientiously carry out allergy tests. In view of the incomplete cross-allergic reaction between cephalosporins and penicillin,