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为研究乙肝患者的肝细胞损害与白细胞介素8(IL-8)及肝细胞刺激物质(HSS)的关系,本文应用ELISA法检测177例乙肝患者血清的IL-8和HSS含量。结果显示:乙肝患者血清的IL-8和HSS水平均较对照组明显升高(P<0.05),且分别与血清ALT水平密切相关(P<0.05),而血清IL-8和HSS含量亦存在相关关系(P<0.05)。揭示IL-8和HSS可能相互影响,并在肝病患者的肝细胞损害、修复和再生中起重要作用
In order to study the relationship between hepatocellular damage and interleukin-8 (IL-8) and hepatocyte stimulating substance (HSS) in hepatitis B patients, the serum levels of IL-8 and HSS in 177 hepatitis B patients were detected by ELISA. The results showed that the levels of serum IL-8 and HSS in patients with hepatitis B were significantly higher than those in controls (P <0.05), and were closely related to serum ALT levels (P <0.05) HSS content is also related (P <0.05). It is revealed that IL-8 and HSS may interact with each other and play an important role in liver cell damage, repair and regeneration in liver disease patients