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目的了解2型糖尿病(T2DM)患者甲状腺结节的患病率及高危因素。方法收集医院住院治疗的T2DM患者106例,总结临床特征及患者一般资料。采用单因素及多因素logistic回归分析相关危险因素。结果T2DM患者甲状腺结节患病率为65.1%,单结节、多结节分别为32.1%、33.0%,两者差异无统计学意义(P>0.05);女性、年龄≥60岁及胰岛素抵抗指数(HOMA-IR)≥1.0是T2DM患者合并甲状腺结节的独立危险因素(P<0.01或P<0.05)。结论 T2DM患者甲状腺结节患病率较高,高龄、女性、胰岛素抵抗者更为突出,临床上有必要对这些患者进行甲状腺结节筛查。
Objective To investigate the prevalence and risk factors of thyroid nodules in type 2 diabetes mellitus (T2DM). Methods A total of 106 T2DM patients hospitalized in our hospital were collected, and the clinical features and general information of the patients were collected. Univariate and multivariate logistic regression analysis of risk factors. Results The prevalence of thyroid nodules in patients with T2DM was 65.1%. The single nodules and multiple nodules were 32.1% and 33.0% respectively. There was no significant difference between the two groups (P> 0.05). Female, age≥60 years and insulin resistance Index (HOMA-IR) ≥1.0 was an independent risk factor for thyroid nodules in patients with T2DM (P <0.01 or P <0.05). Conclusions The prevalence of thyroid nodules in T2DM patients is high, and elderly patients, female patients and insulin resistance patients are more prominent. It is necessary to screen thyroid nodules in these patients clinically.