Preventive and therapeutic effects of NF-kappaB inhibitor curcumin in rats colitis induced by trinit

• 作 者: Yan-TingJian Guo-FengMai Ji-De
• 机 构: ChinesePLAInstituteofDigestiveDisease,JiangmenBoardofHealth,OncologyDepartment
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2005年12期
• 关键词: 核因子-κB 大肠炎 小鼠 动物模型 磺酸三硝基苯 药物治疗 IBD Curcumin TNBS NF-κB
• 基金项目: 中国科学院资助项目，广东省中医药管理局科研项目

AIM: To ascertain the molecule mechanism of nuclear factor-κB (NF-κB) inhibitor curcumin preventive and therapeutic effects in rats' colitis induced by trinitrobenzene sulfonic acid (TNBS).METHODS: Sixty rats with TNBS-induced colitis weretreated with