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目的 为了观察西比灵胶囊对肠易激综合征 (IBS)的临床疗效 ,并探讨其可能的作用机制。方法 采用随机分组法将 164例诊断肠易激综合征的患者分成两组 ,对照组采用乳酸菌素、谷维素、维生素B1口服 ,腹泻型加思密达 ;治疗组在常规治疗基础上加用西比灵。结果 治疗组显效 2 3例 ,有效 5 2例 ,总有效率91.4 6% ,无效 7例 ;对照组显效 14例 ,有效 4 9例 ,总有效率 76.83 % ,无效 19例 ,治疗组疗效明显高于对照组(P <0 0 5 )。结论 肠易激综合征的病因尚未完全阐明 ,应用西比灵治疗肠易激综合征可提高疗效。
Objective To observe the clinical effect of xibiling capsule on irritable bowel syndrome (IBS) and to explore its possible mechanism. Methods One hundred and sixty-four patients with IBS were divided into two groups randomly. The control group was treated with lactic acid bacilli, oryzanol, vitamin B1, and gastramide. The treatment group was given Western medicine spirit. Results In the treatment group, 23 cases were effective and 52 cases were effective. The total effective rate was 91.46%, and 7 cases were ineffective. In the control group, 14 cases were effective and 49 cases were effective. The total effective rate was 76.83% and 19 cases were ineffective. In the control group (P <0 05). Conclusion The etiology of irritable bowel syndrome has not yet been fully elucidated. The application of Sibelink in the treatment of irritable bowel syndrome can improve the curative effect.