论文部分内容阅读
目的采用Meta分析方法探讨出入境人员中HBsAg携带率在不同年龄组之间的差异,为确定重点监测人群提供科学依据。方法以多个独立研究的率差RD值为效应指标,对资料进行异质性检验,以确定采用固定或随机效应模型进行分析;采用漏斗图法检验发表偏倚。结果共收集2003.1～2006.7年间国内公开发表的相关文献9篇,经异质性检验,采用随机效应模型计算合并RD值为-0.02(95%CI-0.03～-0.01,Z=3.31,P<0.01)。结论出入境人员中年龄>30岁组HBsAg携带率高于≤30岁年龄组,这一人群应作为今后的检测重点。
Objective To explore the difference of HBsAg carrier rate among different age groups by means of Meta analysis and to provide a scientific basis for the key monitoring population. Methods Using the rate-of-difference RD values of multiple independent studies as the effect index, the data were tested for heterogeneity to determine the use of fixed or random effects model for analysis. The funnel plot method was used to test publication bias. Results A total of 9 domestic literatures were collected from 2003 to 2006 and 7 years. The heterogeneity test was used to calculate the combined RD value of -0.02 (95% CI -0.03 ~ -0.01, Z = 3.31, P <0.01 ). Conclusion The carrying rate of HBsAg among the immigrants aged> 30 years old is higher than that of ≤30 years old, and this population should be the focus of future testing.