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目的探讨糖尿病合并脑梗死的相关因素。方法选择2006年6月—2014年11月收治的糖尿病合并脑梗死患者共76例作为观察组,选择同期糖尿病无并发脑血管病患者60例作为对照组。收集患者的病史、临床和实验室检查资料,其中检查项目包含入院时的SBP、DBP,血液生化指标含FBG、Hb A1c、TG、TC、HDL-C、LDL-C。计量资料采用t检验,P<0.05为差异有统计学意义。结果观察组糖尿病病程、SBP、FBG、Hb Alc、TG、TC、LDL-C分别为(5.80±3.87)年、(148.76±13.20)mm Hg(1 mm Hg=0.133 k Pa)、(9.41±4.20)mmol/L、(11.31±2.15)%、(7.34±1.81)、(6.84±0.86)、(4.84±1.81)mmol/L,对照组分别为(3.65±2.11)年、(124.62±9.67)mm Hg、(8.17±4.37)mmol/L、(7.06±1.85)%、(4.29±1.76)、(5.04±0.45)、(3.21±2.01)mmol/L,两组比较差异均有统计学意义(均P<0.05)。美国国立卫生研究院脑卒中量表(the national institutes of health stroke scale,NIHSS)评分≤3分的患者Hb A1c为(7.27±1.42)%,NIHSS评分>3分的患者为(9.67±1.68)%,比较差异有统计学意义(P<0.05)。结论在糖尿病合并急性脑卒中的患者中,以缺血性小卒中多见,约占69.7%;糖尿病患者中病程长及高收缩压、高血脂、高Hb A1c更易并发脑梗塞;Hb Alc越高,糖尿病合并脑梗死的神经功能缺损程度越重。
Objective To investigate the related factors of diabetes complicated with cerebral infarction. Methods Sixty-six patients with diabetes mellitus complicated with cerebral infarction from June 2006 to November 2014 were selected as the observation group. Sixty patients with concurrent diabetes mellitus without cerebrovascular disease were selected as the control group. The patient’s medical history, clinical and laboratory data were collected. The test items included SBP, DBP on admission, FBG, Hb A1c, TG, TC, HDL-C and LDL-C in blood biochemical indexes. Measurement data using t test, P <0.05 for the difference was statistically significant. Results The duration of diabetes, SBP, FBG, Hb Alc, TG, TC and LDL-C in the observation group were (5.80 ± 3.87) years, (148.76 ± 13.20) mm Hg ), (11.31 ± 2.15)%, (7.34 ± 1.81), (6.84 ± 0.86) and (4.84 ± 1.81) mmol / L in the control group and (3.65 ± 2.11) and (124.62 ± 9.67) mm Hg was (8.17 ± 4.37) mmol / L, (7.06 ± 1.85)%, (4.29 ± 1.76), (5.04 ± 0.45) and (3.21 ± 2.01) mmol / L, respectively P <0.05). Hb A1c was (7.27 ± 1.42)% in the NIH with the national institutes of health stroke scale (NIHSS) score ≤3, (9.67 ± 1.68)% in the NIHSS score> 3, , The difference was statistically significant (P <0.05). Conclusions Among the patients with acute cerebral apoplexy and diabetes mellitus, most of them are ischemic stroke, accounting for 69.7%. Diabetic patients have long duration and high systolic blood pressure, hyperlipidemia and high Hb A1c with cerebral infarction. The higher Hb Alc , Diabetic patients with cerebral infarction more serious neurological deficit.