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本文报告了我院1981将醋酸纤维膜电泳法用于75例流行性出血热病人尿蛋白分析的做法和结果。其中轻型病人17例,尿蛋白电泳区带0—1条占88.2％;中型14例,尿蛋白区带0～1条占35.7％,2～3条占64.3％;重型34例、危重型10例,尿蛋白区带4～5条分别占67.6％,70.0％。实验结果表明,轻型和中型病人区带少,主要漏出白蛋白;重型和危重型病人区带多,漏出的白蛋白量减少,球蛋白量增多,将醋酸纤维膜电泳法用于尿蛋白分析,对出血热病人的诊断有一定的参考价值。流行性出血热6例动态观察,尿蛋白电泳显示发热后期漏出为白蛋白;极期白蛋白:球蛋白=1:2～1:1;多尿后期或恢复期尿蛋白消失,蛋白区带不出现,说明出血热不同病期,肾脏损害程度不等,对蛋白漏出的选择性也不同。
This article reports our hospital in 1981 will acetate acetate membrane electrophoresis in 75 cases of epidemic hemorrhagic fever patients urine protein analysis practices and results. Among them, 17 cases were light-type patients, 88.2% of 0-1 cases of urinary protein electrophoresis zone, 14 cases of medium-sized, 0 to 1 of 35.7% and 2 to 3 of 64.3% Cases, urinary protein zone 4 to 5 accounted for 67.6%, 70.0%. The experimental results showed that the light and medium patient area less, mainly leaking albumin; heavy and critically ill patients with more zone, the amount of leakage of albumin decreased, the amount of globulin increased, the acetate membrane electrophoresis method for urinary protein analysis, The diagnosis of hemorrhagic fever patients have a certain reference value. Epidemic hemorrhagic fever in 6 cases of dynamic observation, urinary protein electrophoresis showed late release of fever as albumin; very albumin: globulin = 1: 2 ~ 1: 1; urinary protein disappear during the late or convalescent urination, the protein zone is not Appears, indicating different stages of hemorrhagic fever, kidney damage range, the leakage of protein is also different.