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目的了解杭州市健康人群百日咳、白喉、破伤风抗体水平。方法1995～2006年,在不同区(县、市),分2～4岁、6～8岁、13～15岁、25～39岁4个年龄组开展百日咳、白喉、破伤风抗体监测。结果百日咳抗体共监测1942人,保护率为93.87%,几何平均摘度为1∶1037.36。其中农村2～4岁保护率低于其它三个年龄组,与6～8岁、13～15岁组保护率差异有非常显著的统计学意义(χ2=8.80、6.13;P均<0.01)。白喉抗体监测2141人,阳性率91.59%,几何平均浓度(GMC)为0.291国际单位/毫升(IU/ml)。破伤风抗体监测2141人,阳性率72.35%,GMC为0.095IU/ml。结论应加强农村地区的免疫规划管理及预防接种工作。
Objective To understand the levels of pertussis, diphtheria and tetanus in healthy population in Hangzhou. Methods From 1995 to 2006, pertussis, diphtheria and tetanus antibodies were detected in 4 age groups of 2 ~ 4 years, 6 ~ 8 years, 13 ~ 15 years and 25 ~ 39 years in different districts (counties and cities). Results A total of 1942 persons were tested for pertussis antibodies with a protection rate of 93.87% and a geometric mean cutoff of 1:1037.36. Among them, the protection rate of 2 ~ 4 years old in rural areas was lower than that of the other three age groups. There was a significant difference between the protection rates of 6 ~ 8 years old and 13 ~ 15 years old group (χ2 = 8.80,6.13; P <0.01). Diphtheria antibody surveillance 2141 people, the positive rate of 91.59%, the geometric mean concentration (GMC) of 0.291 International Units / ml (IU / ml). The number of tetanus antibody surveillance was 2141, the positive rate was 72.35%, GMC was 0.095IU / ml. Conclusion The immunization program management and vaccination should be strengthened in rural areas.